| саморазрушающая генная терапия | suicide gene therapy (We used an adenovirus, similar to the one that causes the common cold, to carry the therapy agent–a herpes virus gene that produces the enzyme thymidine kinase, or TK–directly into the tumor cells. Once the herpes virus gene was delivered and it started manufacturing TK, we gave patients a commonly used anti-herpes drug, valacyclovir. The combination attacked the herpes DNA, and the TK-producing tumor cells self-destructed, which is why the procedure is called "suicide gene therapy." Alex_Odeychuk) |
