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depyrogenation (вещества, которые при попадании в кровь вызывают подъем температуры; их удаляют при производстве растворов, предназначенных для парентерального введения: Depyrogenation refers to the removal of pyrogens from solutions, most commonly from injectable pharmaceuticals. A pyrogen is defined as any substance that can cause a fever. Bacterial pyrogens include endotoxins and exotoxins, although many pyrogens are endogenous to the host. Natalyya); pyrogen removal (Pyrogen removal (depyrogenation) – Pyrogens can often be difficult to remove from solution due to the high variability of their molecular weight. Pyrogens are also relatively thermally stable and insensitive to pH changes. However, several removal techniques exist wikipedia.org 'More) |